GH

Growth hormone (GH)

Growth hormone (GH) is a 191-amino acid, single-chain polypeptide that is synthesized, stored, and secreted by somatotropic cells within the lateral wings of the anterior pituitary gland. It stimulates growth, cell reproduction and regeneration in humans and other animals. It is a stress hormone that raises the concentration of glucose and free fatty acids. Secretion of GH in the pituitary is regulated by the hypothalamus. These cells release the peptides GHRH and GHIH into the hypophyseal portal venous blood surrounding the pituitary.. A number of factors are known to affect GH secretion, such as age, sex, diet, exercise, stress, and other hormones.

 

 

GH excess

  • GH helps to monitor the pituitary tumor in the gigantism and acromegaly.

GH deficiency

  • Diagnose of GH deficiency in children to evaluate the midgetism.
  • GH is used as a prescription drug in medicine to treat children’s growth disorders and adult growth hormone deficiency
(GH) C APPGrowth hormone secretion in the normal and acromdgaly

                                               GH Serum Sample

Catalog Number SDC5451
Reagent Pack 100
Principle Automated Chemiluminescence Immunoassay(CLIA)
Sensitivity 0.05ng/mL
Dynamic range  0.50-50 ng/mL
Sample Type Serum
Intra-assay precision 5.87%
Inter-assay precision 8.85%
Sample Volume 20 μL

SDi CX GH vs. SIEMENS Immulite GH Test

A comparison of SIMENES Immulite 2000 GH with SDi CX GH using clinical samples gave the following correlations (ng/mL):

y = 0.924x – 0.070

R² = 0.984

Samples measured: 101

GH M CO