25-OH Vitamin D

Vitamin D is a group of fat-soluble secosteroids.Vitamin D2 (Ergocalciferol)and vitamin 03 (Cholecalciferol) are two major forms of Vitamin D in human body.
25-0H Vitamin D (25-hydroxyvitami n D, also known as Calcifediol), is a prehormone that is produced in the liver by hydroxylation of Vitamin D by the enzyme cholecalciferol 25-hydroxylase. Then, 25-0H Vitamin D is convert into Calcitriol (1,25-(0H)2 D3 ) in the kidneys, a secosteroid hormone that is the active form of vitamin D.
Vitamin D is multiple- function hormone for maintaining body health. It regulated the Calcium and Phosphorus concentration in Bone metabolism. It also plays a very important role in other systems of human body, such as preventing cancer, protecting cardiovascular system, preventing diabetes, promoting cell proliferation.
25-0H Vitamin D blood test is used to determine the Vitamin D level in the body. The blood concentration of 25-0H Vitamin D is considered the best indicator of vitamin D status.
Major Source of Vitamin D

  • Vitamin D3: Conversed from 7-dehydrogenation cholesterol in the upper layer of the skin during UV Exposure, partly taken from food.
  • Vitamin D2: Taken from food such as vegetables and fugues.

Vit D 1

Bone metabolism:

  • Diagnosis of nutritional Vitamin  D deficiency (rickets)
  • Diagnosis of Osteoporosis caused by the deficiency of Vitamin D
  • Diagnosis of Secondary parathyroid hyperthyroidism
  • Monitor the pregnancy and neonatus hypocalcemia
  • Other uses: Vitamin D and Cardiovascular system disease

  • Vitamin D can downgrade the activity of RAAS (Rein-Angiotensin-Aldosterone system).
  • Vitamin D can prevent myocardial hypertrophy and myocardial dysfunction.
  • Vitamin D can prevent inflammation mediated atherosclerosis and vasodilatation dysfunction.
  • Vitamin D and Diabetes

  • High level of Vitamin D can reduce the risk of Diabetes II, maintaining level of Vitamin D could prevent Diabetes II.

Vitamin D and Tumorigenesis

  • VD defiance may raise the risk of colon cancer, breast cancer, ovarian cancer, and prostatic cancer.

Vitamin D and Immunologic Diseases

  • VD defiance may cause acquired immunologic diseases and autoimmune diseases

                                    25-OH Vitamin D Serum Sample Serum Sample

Catalog Number SDC5348
Reagent Pack    100
Principle Automated Chemiluminescence Immunoassay(CLIA)
Sample Type Serum
Dynamic range       30-100 ng/ml
Sample Type  Serum
Sample Volume   100 μL
Sensitivity   <3.0 ng/ml